Publicaciones – Autores

Reguera RM, Elmahallawy EK, Garcia-Estrada C, Carbajo-Andrés R, Balana-Fouce R.

  • DNA Topoisomerases of Leishmania parasites; druggable targets for drug discovery.
  • Current Medicinal Chemistry, 2018, 25,
  • doi: 10.2174/0929867325666180518074959.

Carballeira NM, Morales-Guzman C, Alvarez-Benedicto E, Torres-Martinez Z, Delgado-Reyes Y, Griebenow KH, Tinoco AD, Reguera RM, Perez-Pertejo Y, Carbajo-Andres R, Balana-Fouce R.

  • First Total Synthesis of -Phenyl 6 Fatty Acids and their Leishmanicidal and Anticancer Properties.
  • Current Topics in Medicinal Chemistry, 2018 May 16.
  • doi: 10.2174/1568026618666180516125056.

Chander S, Ashok P, Reguera RM, Perez-Pertejo MY, Carbajo-Andres R, Balana-Fouce R, Gowri Chandra Sekhar KV, Sankaranarayanan M.

  • Synthesis and activity of benzopiperidine, benzopyridine and phenyl piperazine based compounds against Leishmania infantum.
  • Experimental Parasitology 2018, 189, 49-60.
  • doi: 10.1016/j.exppara.2018.04.017.

Tejería A, Pérez-Pertejo Y, Reguera RM, Balaña-Fouce R, Alonso C, González M, Rubiales G, Palacios F.

  • Substituted 1, 5-naphthyridine derivatives as novel antileishmanial agents. Synthesis and biological evaluation.
  • European Journal of Medicinal Chemistry 2018, 152, 137-147.
  • doi: 10.1016/j.ejmech.2018.04.033.

García-Calvo L, Ullán RV, Fernández-Aguado M, García-Lino AM, Balaña-Fouce R, Barreiro C.

  • Secreted protein extract analyses present the plant pathogen Alternaria alternata as a suitable industrial enzyme toolbox.
  • Journal of Proteomics, 2018, 177, 48-64.
  • doi: 10.1016/j.jprot.2018.02.012.

Gutierrez-Corbo C, Dominguez-Asenjo, B, Vossen, LI, Pérez-Pertejo, Y, Muñoz-Fenández, MA, Balaña-Fouce, R, Calderón M, Reguera RM.

  • Pegylated dendritic polyglycerol conjugate delivers doxorubicin to the parasitophorous vacuole in Leishmania infantum infections.
  • Macromolecular Bioscience, 2017, 17(10).
  • doi: 10.1002/mabi.201700098.

Escudero-Martínez JM, Pérez-Pertejo Y, Reguera RM, Castro MA, Rojo MV, Santiago C, Abad A, García PA, López-Pérez JL, San Feliciano A, Balaña-Fouce R.

  • Antileishmanial activity and tubulin polymerization inhibition of podophyllotoxin derivatives on Leishmania infantum.
  • International Journal for Parasitology-Drugs and Drug Resistance, 2017, 7, 272-285.
  • doi: 10.1016/j.ijpddr.2017.06.003.

Tejería A, Pérez-Pertejo Y, Reguera RM, Balaña-Fouce R, Alonso C, Fuertes M, González M, Rubiales G, Palacios F.

  • Antileishmanial effect of new indeno-1,5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase.
  • European Journal of Medicinal Chemistry 2016, 124, 740-749.
  • doi: 10.1016/j.ejmech.2016.09.017.

Iborra S, Martínez-López M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martín Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, Sancho D.

  • Leishmania uses mincle to target an inhibitory ITAM signaling pathway in dendritic cells that dampens adaptive immunity to infection.
  • Immunity. 2016, 45(4), 788-801.
  • doi: 10.1016/j.immuni.2016.09.012.

Perisé-Barrios AJ, Fuentes-Paniagua E, Sánchez-Nieves J, Serramía MJ, Alonso E, Reguera RM, Gómez R, de la Mata FJ, Muñoz-Fernández MÁ.

  • Improved efficiency of Ibuprofen by cationic carbosilane dendritic conjugates.
  • Molecular Pharmacology 2016,13(10),3427-3438.

Reguera RM, Morán M, Pérez-Pertejo Y, García-Estrada C, Balaña-Fouce R.

  • Current status on prevention and treatment of canine leishmaniasis.
  • Veterinary Parasitology, 2016, 227, 98-114.
  • doi: 10.1016/j.vetpar.2016.07.011.

Balaña-Fouce, R.; Reguera, R.M.

  • Yeast-based systems for tropical disease drug discovery.
  • Expert Opinion on Drug Discovery, 2016, 11, 429-432.
  • doi: 10.1517/17460441.2016.1160052.

Carballeira NM, Montano N, Amador LA, Rodríguez AD, Golovko MY, Golovko SA, Reguera RM, Álvarez-Velilla R, Balaña-Fouce R. (2016).

  • Novel very long-chain α-methoxylated Δ5,9 fatty acids from the sponge Asteropus niger are effective inhibitors of topoisomerases IB.
  • Lipids, 2016, 51, 245-256.
  • doi: 10.1007/s11745-015-4114-9.

Gutiérrez V, Seabra AB, Reguera RM, Khandare J, Calderón M.

  • New approaches from nanomedicine for treating leishmaniasis.
  • Chemical Society Reviews 2016,45(1),152-68.
  • doi: 10.1039/c5cs00674k.

Calvo-Álvarez E, Stamatakis K, Punzón C, Álvarez-Velilla R, Tejería A, Escudero-Martínez JM, Pérez-Pertejo Y, Fresno M, Balaña-Fouce R, Reguera RM.

  • Infrared fluorescent imaging as a potent tool for in vitro, ex vivo and in vivo models of visceral leishmaniasis.
  • PLoS Neglected Tropical Diseases 2015 Mar 31;9(3):e0003666.
  • doi: 10.1371/journal.pntd.0003666.

Calvo-Álvarez E, Álvarez-Velilla R, Fernández-Prada C, Balaña-Fouce R, Reguera RM.

  • Trypanosomatids see the light: recent advances in bioimaging research.
  • Drug Discovery Today. 2015 Jan;20(1):114-21.
  • doi: 10.1016/j.drudis.2014.09.012.

Calvo-Álvarez E, Álvarez-Velilla R, Jiménez M, Molina R, Pérez-Pertejo Y, Balaña-Fouce R, Reguera RM.

  • First evidence of intraclonal genetic exchange in trypanosomatids using two Leishmania infantum fluorescent transgenic clones.
  • PLoS Neglected Tropical Diseases. 2014, 8(9), e3075.
  • doi: 10.1371/journal.pntd.0003075.

Balaña-Fouce R, Alvarez-Velilla R, Fernández-Prada C, García-Estrada C, Reguera RM.

  • Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery.
  • International Journal for Parasitology-Drugs and Drug Resistance, 2014, 4(3),326-37.
  • doi: 10.1016/j.ijpddr.2014.07.006.

Reguera RM, Calvo-Álvarez E, Alvarez-Velilla R, Balaña-Fouce R.

  • Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?
  • International Journal for Parasitology-Drugs and Drug Resistance, 2014, 4(3),355-7.
  • doi: 10.1016/j.ijpddr.2014.05.001.

Carballeira NM, Montano N, Alvarez-Velilla R, Prada CF, Reguera RM, Balaña-Fouce R.

  • Synthesis of marine α-methoxylated fatty acid analogs that effectively inhibit the topoisomerase IB from Leishmania donovani with a mechanism different from that of camptothecin.
  • Marine Drugs. 2013, 11(10), 3661-75.
  • doi: 10.3390/md11103661.

Prada CF, Álvarez-Velilla R, Díaz-Gozález R, Pérez-Pertejo Y, Balaña-Fouce R, Reguera RM.

  • Identification and characterization of the regions involved in the nuclear translocation of the heterodimeric leishmanial DNA topoisomerase IB.
  • PLoS One. 2013 Sep 2;8(9):e73565.
  • doi: 10.1371/journal.pone.0073565.

Prada CF, Alvarez-Velilla R, Balaña-Fouce R, Prieto C, Calvo-Álvarez E, Escudero-Martínez JM, Requena JM, Ordóñez C, Desideri A, Pérez-Pertejo Y, Reguera RM.

  • Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect.
  • Biochemical Pharmacology. 2013, 85(10),1433-40.
  • doi: 10.1016/j.bcp.2013.02.024.

Rastrojo A, Carrasco-Ramiro F, Martín D, Crespillo A, Reguera RM, Aguado B, Requena JM.

  • The transcriptome of Leishmania major in the axenic promastigote stage: transcript annotation and relative expression levels by RNA-seq.
  • BMC Genomics. 2013, 14, 223.
  • doi: 10.1186/1471-2164-14-223.

Calvo-Álvarez E, Guerrero NA, Alvarez-Velilla R, Prada CF, Requena JM, Punzón C, Llamas MÁ, Arévalo FJ, Rivas L, Fresno M, Pérez-Pertejo Y, Balaña-Fouce R, Reguera RM.

  • Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis.
  • PLoS Neglected Tropical Diseases. 2012,6(11),e1927.
  • doi: 10.1371/journal.pntd.0001927.

González B, Garrido F, Ortega R, Martínez-Júlvez M, Revilla-Guarinos A, Pérez-Pertejo Y, Velázquez-Campoy A, Sanz-Aparicio J, Pajares MA.

  • NADP+ binding to the regulatory subunit of methionine adenosyltransferase II increases intersubunit binding affinity in the hetero-trimer.
  • PLoS One. 2012,7(11),e50329.
  • doi: 10.1371/journal.pone.0050329

Balaña-Fouce R, Prada CF, Requena JM, Cushman M, Pommier Y, Álvarez-Velilla R, Escudero-Martínez JM, Calvo-Álvarez E, Pérez-Pertejo Y, Reguera RM.

  • Indotecan (LMP400) and AM13-55: two novel indenoisoquinolines show potential for treating visceral leishmaniasis.
  • Antimicrobial Agents Chemotherapy. 2012,56(10),5264-70.
  • doi: 10.1128/AAC.00499-12.

Prada CF, Alvarez-Velilla R, Diaz-González R, Prieto C, Pérez-Pertejo Y, Balaña-Fouce R, Reguera RM.

  • A pentapeptide signature motif plays a pivotal role in Leishmania DNA topoisomerase IB activity and camptothecin sensitivity.
  • Biochimica et Biophysica Acta. 2012,1820(12),2062-71.
  • doi: 10.1016/j.bbagen.2012.09.005.

Carballeira NM, Cartagena M, Sanabria D, Tasdemir D, Prada CF, Reguera RM, Balaña-Fouce R.

  • 2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani.
  • Bioorganic Medicinal Chemistry Letters. 2012,22(19),6185-9.
  • doi: 10.1016/j.bmcl.2012.08.019.

Carballeira NM, Cartagena M, Li F, Chen Z, Prada CF, Calvo-Alvarez E, Reguera RM, Balaña-Fouce R.

  • First total synthesis of the (±)-2-methoxy-6-heptadecynoic acid and related 2-methoxylated analogs as effective inhibitors of the leishmania topoisomerase IB enzyme.
  • Pure and Applied Chemistry. 2012,84(9),1867-1875.

Balaña-Fouce R, Calvo-Álvarez E, Álvarez-Velilla R, Prada CF, Pérez-Pertejo Y, Reguera RM.

  • Role of trypanosomatid's arginase in polyamine biosynthesis and pathogenesis.
  • Molecular and Biochemical Parasitology. 2012,181(2),85-93.
  • doi: 10.1016/j.molbiopara.2011.10.007.

Pérez-Pertejo Y, Alvarez-Velilla R, Estrada CG, Balaña-Fouce R, Reguera RM.

  • Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase.
  • Parasitology. 2011,138(9),1082-92.
  • doi: 10.1017/S0031182011000862.

Carballeira NM, Montano N, Reguera RM, Balaña-Fouce R.

  • The first total synthesis of the (±)-17-methyl-trans-4,5-methyleneoctadecanoic acid and related analogs with antileishmanial activity.
  • Tetrahedron Letters. 2010,51(47),6153-6155.

Carballeira NM, Montano N, Cintrón GA, Márquez C, Rubio CF, Prada CF, Balaña-Fouce R.

  • First total synthesis and antileishmanial activity of (Z)-16-methyl-11-heptadecenoic acid, a new marine fatty acid from the sponge Dragmaxia undata.
  • Chemistry and Physics of Lipids. 2011,164(2),113-7.
  • doi: 10.1016/j.chemphyslip.2010.11.006.

García-Estrada C, Prada CF, Fernández-Rubio C, Rojo-Vázquez F, Balaña-Fouce R.

  • DNA topoisomerases in apicomplexan parasites: promising targets for drug discovery.
  • Proceedings of the Royal Society. 2010,277(1689),1777-87.
  • doi: 10.1098/rspb.2009.2176.

Muleme HM, Reguera RM, Berard A, Azinwi R, Jia P, Okwor IB, Beverley S, Uzonna JE.

  • Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease pathogenesis.
  • Journal of Immunology. 2009,183(12),8068-76.
  • doi: 10.4049/jimmunol.0803979.

Carballeira NM, Cartagena MM, Prada CF, Rubio CF, Balaña-Fouce R.

  • Total synthesis and antileishmanial activity of the natural occurring acetylenic fatty acids 6-heptadecynoic acid and 6-icosynoic acid.
  • Lipids. 2009,44(10),953-61.
  • doi: 10.1007/s11745-009-3345-z.

Carballeira NM, Montano N, Balaña-Fouce R, Prada CF.

  • First total synthesis and antiprotozoal activity of (Z)-17-methyl-13-octadecenoic acid, a new marine fatty acid from the sponge Polymastia penicillus.
  • Chemistry and Physics of Lipids. 2009 Sep;161(1):38-43.
  • doi: 10.1016/j.chemphyslip.2009.06.140.

Ordóñez C, Alfonso J, Balaña-Fouce R, Ordóñez D.

  • Functional expression of a DNA-topoisomerase IB from Cryptosporidium parvum.
  • Journal of Biomedicine and Biotechnology. 2009, 2009,837608.
  • doi: 10.1155/2009/837608.

Díaz-González R, Pérez-Pertejo Y, Prada CF, Fernández-Rubio C, Balaña-Fouce R, Reguera RM.

  • Novel findings on trypanosomatid chemotherapy using DNA topoisomerase inhibitors.
  • Mini Reviews in Medicinal Chemistry. 2009,9(6),674-86.

Fernández-Rubio C, Ordóñez C, Abad-González J, Garcia-Gallego A, Honrubia MP, Mallo JJ, Balaña-Fouce R.

  • Butyric acid-based feed additives help protect broiler chickens from Salmonella Enteritidis infection.
  • Poultry Science. 2009, 88(5),943-8.
  • doi: 10.3382/ps.2008-00484.

Reguera RM, Balaña-Fouce R, Showalter M, Hickerson S, Beverley SM.

  • Leishmania major lacking arginase (ARG) are auxotrophic for polyamines but retain infectivity to susceptible BALB/c mice.
  • Molecular and Biochemical Parasitology. 2009,165(1),48-56.
  • doi: 10.1016/j.molbiopara.2009.01.001.

Reguera RM, Díaz-González R, Pérez-Pertejo Y, Balaña-Fouce R.

  • Characterizing the bi-subunit type IB DNA topoisomerase of Leishmania parasites; a novel scenario for drug intervention in trypanosomatids.
  • Current Drug Targets. 2008, 9(11),966-78.

Balaña-Fouce R, García-Estrada C, Pérez-Pertejo Y, Reguera RM.

  • Gene disruption of the DNA topoisomerase IB small subunit induces a non-viable phenotype in the hemoflagellate Leishmania major.
  • BMC Microbiology. 2008, 8, 113.
  • doi: 10.1186/1471-2180-8-113.

Diaz-González R, Pérez-Pertejo Y, Pommier Y, Balaña-Fouce R, Reguera RM.

  • Mutational study of the "catalytic tetrad" of DNA topoisomerase IB from the hemoflagellate Leishmania donovani: Role of Asp-353 and Asn-221 in camptothecin resistance.
  • Biochemical Pharmacology. 2008,76(5),608-19.
  • doi: 10.1016/j.bcp.2008.06.019.

García-Estrada C, Pérez-Pertejo Y, Ordóñez D, Balaña-Fouce R, Reguera RM.

  • Characterization of the 5' region of the Leishmania infantum LORIEN/MAT2 gene cluster and role of LORIEN flanking regions in post-transcriptional regulation.
  • Biochimie. 2008, 90(9),1325-36.
  • doi: 10.1016/j.biochi.2008.03.007.

Díaz González R, Pérez Pertejo Y, Ordóñez D, Balaña-Fouce R, Reguera RM.

  • Deletion study of DNA topoisomerase IB from Leishmania donovani: searching for a minimal functional heterodimer.
  • PLoS One. 2007, 2(11), e1177.

Pérez-Pertejo Y, Reguera RM, Ordóñez D, Balaña-Fouce R.

  • Alterations in the glutathione-redox balance induced by the bio-insecticide Spinosad in CHO-K1 and Vero cells.
  • Ecotoxicology and Environmental Safety. 2008, 70(2),251-8.

Díaz González R, Pérez Pertejo Y, Redondo CM, Pommier Y, Balaña-Fouce R, Reguera RM.

  • Structural insights on the small subunit of DNA topoisomerase I from the unicellular parasite Leishmania donovani.
  • Biochimie. 2007,89(12),1517-27.

Balaña-Fouce R, Reguera RM.

  • RNA interference in Trypanosoma brucei: a high-throughput engine for functional genomics in trypanosomatids?
  • Trends in Parasitology. 2007, 23(8), 348-51.

Reguera RM, Pérez-Pertejo Y, Redondo CM, Díaz-González R, Balaña-Fouce R.

  • Type I DNA topoisomerase from protozoan pathogens as a potential target for anti-tumoral drugs.
  • Medicina (Buenos Aires). 2007,67(6 Pt 2),747-57.

Reguera RM, Redondo CM, Pérez-Pertejo Y, Balaña-Fouce R.

  • S-Adenosylmethionine in protozoan parasites: functions, synthesis and regulation.
  • Molecular and Biochemical Parasitology. 2007,152(1),1-10.

García-Estrada C, Pérez-Pertejo Y, Ordóñez D, Balaña-Fouce R, Reguera RM.

  • Analysis of genetic elements regulating the methionine adenosyltransferase gene in Leishmania infantum.
  • Gene. 2007, 389(2),163-73.

Balaña-Fouce R, Redondo CM, Pérez-Pertejo Y, Díaz-González R, Reguera RM.

  • Targeting atypical trypanosomatid DNA topoisomerase I.
  • Drug Discovery Today. 2006,11(15-16),733-40.

Reguera RM, Redondo CM, Gutierrez de Prado R, Pérez-Pertejo Y, Balaña-Fouce R.

  • DNA topoisomerase I from parasitic protozoa: a potential target for chemotherapy.
  • Biochimica et Biophysica Acta. 2006, 1759(3-4),117-31.

Pérez-Pertejo Y, Reguera RM, Ordóñez D, Balaña-Fouce R.

  • Characterization of a methionine adenosyltransferase over-expressing strain in the trypanosomatid Leishmania donovani.
  • Biochimica et Biophysica Acta. 2006,1760(1),10-9.

García-Fernández AJ, Rodríguez RA, Pérez-Pertejo Y, Balaña-Fouce R.

  • Characterization of putrescine uptake in hamster amelanocytic melanoma AMEL-3 cells.
  • Molecules and Cells. 2005, 20(1), 127-35.

Reguera RM, Tekwani BL, Balaña-Fouce R.

  • Polyamine transport in parasites: a potential target for new antiparasitic drug development.
  • Comparative Biochemistry and Physiology C Toxicology and Pharmacology. 2005, 140(2),151-64.

Abdel-Ghani SB, Martinez-Lopez E, Pérez-Pertejo Y, Bayoumi AE, Garcia-Fernandez A, Balaña-Fouce R, Ordóñez D.

  • Cytotoxicity and mutagenicity of four insect pheromones in CHO-K1 cells.
  • Bulletin of Environmental Contamination and Toxicology. 2004 Dec;73(6):963-70.

Pérez-Pertejo Y, Reguera RM, García-Estrada C, Balaña-Fouce R, Ordóñez D.

  • Mutational analysis of methionine adenosyltransferase from Leishmania donovani.
  • European Journal of Biochemistry. 2004, 271(13),2791-8.

Villa H, Pérez-Pertejo Y, García-Estrada C, Reguera RM, Requena JM, Tekwani BL, Balaña-Fouce R, Ordóñez D.

  • Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani.
  • European Journal of Biochemistry. 2003, 270(21),4339-47.

García-Estrada C, Reguera RM, Villa H, Requena JM, Müller S, Pérez-Pertejo Y, Balaña-Fouce R, Ordóñez D.

  • Identification of a gene in Leishmania infantum encoding a protein that contains a SP-RING/MIZ zinc finger domain.
  • Biochimica et Biophysica Acta. 2003 Oct 1;1629(1-3):44-52

Bayoumi AE, Pérez-Pertejo Y, Zidan HZ, Balaña-Fouce R, Ordóñez C, Ordóñez D.

  • Cytotoxic effects of two antimolting insecticides in mammalian CHO-K1 cells.
  • Ecotoxicology and Environmental Safety. 2003 May;55(1):19-23.

Villa H, Otero Marcos AR, Reguera RM, Balaña-Fouce R, García-Estrada C, Pérez-Pertejo Y, Tekwani BL, Myler PJ, Stuart KD, Bjornsti MA, Ordóñez D.

  • A novel active DNA topoisomerase I in Leishmania donovani.
  • Journal of Biological Chemistry. 2003 Feb 7;278(6):3521-6.

Pérez-Pertejo Y, Reguera RM, Villa H, García-Estrada C, Balaña-Fouce R, Pajares MA, Ordóñez D.

  • Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme.
  • European Journal of Biochemistry. 2003 Jan;270(1):28-35.

García-Fernández AJ, Bayoumi AE, Pérez-Pertejo Y, Romero D, Ordóñez C, Reguera RM, Balaña-Fouce R, Ordóñez D.

  • Changes in glutathione-redox balance induced by hexachlorocyclohexane and lindane in CHO-K1 cells.
  • Xenobiotica. 2002 Nov;32(11):1007-16.

García-Fernández AJ, Bayoumi AE, Pérez-Pertejo Y, Motas M, Reguera RM, Ordóñez C, Balaña-Fouce R, Ordóñez D.

  • Alterations of the glutathione-redox balance induced by metals in CHO-K1 cells.
  • Comparative Biochemistry and Physiology C Toxicology and Pharmacology. 2002 Jul;132(3):365-73.

Bayoumi AE, Ordóñez C, Pérez-Pertejo Y, Zidan HZ, Balaña-Fouce R, Reguera RM, Ordóñez Escudero D.

  • Basal cytotoxicity of four insect sex pheromones in CHO-K1 cells.
  • Bulletin of Environmental Contamination and Toxicology. 2002 Feb;68(2):302-8.

Reguera RM, Balaña-Fouce R, Pérez-Pertejo Y, Fernández FJ, García-Estrada C, Cubría JC, Ordóñez C, Ordóñez D.

  • Cloning expression and characterization of methionine adenosyltransferase in Leishmania infantum promastigotes.
  • Journal of Biological Chemistry. 2002 Feb 1;277(5):3158-67.

Bayoumi AE, García-Fernández AJ, Ordóñez C, Pérez-Pertejo Y, Cubría JC, Reguera RM, Balaña-Fouce R, Ordóñez D.

  • Cyclodiene organochlorine insecticide-induced alterations in the sulfur-redox cycle in CHO-K1 cells.
  • Comparative Biochemistry and Physiology C Toxicology and Pharmacology. 2001 Nov;130(3):315-23.

Picó Y, Font G, Balaña-Fouce R, Ordóñez C, Abbas D, Barbe J.

  • Analysis of pyridoquinoline derivatives by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry.
  • Rapid Communications in Mass Spectrometry. 2001;15(11):862-6.

Bayoumi AE, Pérez-Pertejo Y, Ordóñez C, Reguera RM, Balaña-Fouce R, Ordóñez D.

  • Changes in the glutathione-redox balance induced by the pesticides heptachlor, chlordane, and toxaphene in CHO-K1 cells.
  • Bulletin of Environmental Contamination and Toxicology. 2000 Dec;65(6):748-55.

Bayoumi AE, Perez-Pertejo Y, Ordóñez C, Reguera RM, Cubría JC, Balaña-Fouce R, Ordóñez D.

  • Alterations on polyamine content and glutathione metabolism induced by different concentrations of paraquat in CHO-K1 cells.
  • Toxicology In Vitro. 2000 Jun;14(3):211-7.

Cepero M, Pérez-Pertejo Y, Cubría JC, Reguera R, Balaña-Fouce R, Ordóñez C, Ordóñez Escudero D.

  • Muscle and serum changes with salbutamol administration in aerobically exercised rats.
  • Comparative Biochemistry and Physiology C Toxicology and Pharmacology. 2000 May;126(1):45-51.

Reguera RM, Pérez-Pertejo Y, Ordóñez C, Cubría JC, Tekwani BL, Balaña-Fouce R, Ordóñez D.

  • S-adenosylmethionine synthesis in Leishmania infantum promastigotes.
  • Cell Biology International. 1999;23(8):579-83.

Cubría JC, Ordóñez C, Reguera RM, Tekwani BL, Balaña-Fouce R, Ordóñez D.

  • Early alterations of polyamine metabolism induced after acute administration of clenbuterol in mouse heart.
  • Life Sciences. 1999;64(19):1739-52.

Cepero M, Cubría JC, Reguera R, Balaña-Fouce R, Ordóñez C, Ordóñez D.

  • Plasma and muscle polyamine levels in aerobically exercised rats treated with salbutamol.
  • Journal of Pharmacy Pharmacology. 1998 Sep;50(9):1059-64.

Johnson R, Cubría JC, Reguera RM, Balaña-Fouce R, Ordóñez D.

  • Interaction of cationic diamidines with Leishmania infantum DNA.
  • Biological Chemistry. 1998 Jul;379(7):925-30.

Cubría JC, Reguera R, Balaña-Fouce R, Ordóñez C, Ordóñez D.

  • Polyamine-mediated heart hypertrophy induced by clenbuterol in the mouse.
  • Journal of Pharmacy Pharmacology. 1998 Jan;50(1):91-6.

Navas IM, García-Fernández AJ, Johnson RA, Reguera RM, Balaña-Fouce R, Ordóñez D.

  • Structural determinants of putrescine uptake inhibition produced by cationic diamidines in the model of trypanosomatid Crithidia fasciculata.
  • Biological Chemistry. 1996 Dec;377(12):833-6.

Calonge M, Johnson R, Balaña-Fouce R, Ordóñez D.

  • Effects of cationic diamidines on polyamine content and uptake on Leishmania infantum in in vitro cultures.
  • Biochemical Pharmacology. 1996 Sep 27;52(6):835-41.

Calonge M, Cubría JC, Balaña-Fouce R, Ordóñez D.

  • Putrescine active uptake system in the Trypanosomatid Crithidia fasciculata.
  • Biological Chemistry Hoppe Seyler. 1996 Apr;377(4):233-8.

Kandpal M, Fouce RB, Pal A, Guru PY, Tekwani BL.

  • Kinetics and molecular characteristics of arginine transport by Leishmania donovani promastigotes.
  • Molecular and Biochemical Parasitology. 1995 May;71(2):193-201.

Reguera RM, Fouce RB, Cubría JC, Bujidos ML, Ordóñez D.

  • Fluorinated analogues of L-ornithine are powerful inhibitors of ornithine decarboxylase and cell growth of Leishmania infantum promastigotes.
  • Life Sciences. 1995;56(4):223-30.

Parry L, Balaña Fouce R, Pegg AE.

  • Post-transcriptional regulation of the content of spermidine/spermine N1-acetyltransferase by N1N12-bis(ethyl)spermine.
  • Biochemical Journal. 1995 Jan 15;305 ( Pt 2):451-8.

del Estal JL, Alvarez-Bujidos ML, Balaña Fouce R, Ordóñez D, Prieto JG.

  • The intestinal absorption of Luxabendazole in rats.
  • Journal of Pharmaceutical and Biomedical Analysis. 1994 Nov;12(11):1471-4.

Reguera R, Balaña Fouce R, Cubria JC, Alvarez Bujidos ML, Ordoñez D.

  • Putrescine uptake inhibition by aromatic diamidines in Leishmania infantum promastigotes.
  • Biochemical Pharmacology. 1994 May 18;47(10):1859-66.

Cubria JC, Balaña-Fouce R, Ortiz A, Alvarez-Bujidos ML, Ordoñez D. Selective inhibition of mammalian diamine oxidase by aquatic biotoxins.

  • Toxicology In Vitro. 1993 Sep;7(5):669-71.

Cubría JC, Balaña Fouce R, Alvarez-Bujidos ML, Negro A, Ortiz AI, Ordóñez D.

  • Aromatic diamidines are reversible inhibitors of porcine kidney diamine oxidase.
  • Biochemical Pharmacology. 1993 Mar 24;45(6):1355-7.

Alvarez-Bujidos ML, Ortiz A, Balaña R, Cubría JC, Ordoñez D, Negro A.

  • Determination of luxabendazole in biological fluids by high-performance liquid chromatography.
  • Journal of Chromatography. 1992 Jul 24;578(2):321-6.

Balaña Fouce R, Escribano MI, Alunda JM.

  • Putrescine uptake regulation in response to alpha-difluoromethylornithine treatment in Leishmania infantum promastigotes.
  • Molecular and Cellular Biochemistry. 1991 Oct 16;107(2):127-33.

Fernandez GM, Lumbreras JM, Balana R, Ordonez D.

  • Possible biotransformation mechanism of 3-aminopropionitrile by means of free radicals.
  • Veterinary and Human Toxicology. 1991 Aug;33(4):321-4.

Balaña-Fouce R, Escribano MI, Alunda JM.

  • Leishmania infantum: polyamine biosynthesis and levels during the growth of promastigotes.
  • International Journal of Biochemistry. 1991;23(11):1213-7.

Fernandez GM, Lumbreras JM, Balaña R, Ordoñez D.

  • Production of cyanide in the rat liver from 3-aminopropionitrile.
  • Journal De Toxicologie Clinique Et Experimentale. 1990 Mar-Apr;10(2):67-71.

Balaña-Fouce R, Ordóñez D, Alunda JM.

  • Putrescine transport system in Leishmania infantum promastigotes.
  • Molecular and Biochemical Parasitology. 1989 Jun 1;35(1):43-50.

Sànchez M, Alvarez MA, Balaña R, Garrido-Pertierra A.

  • Properties and functions of two succinic-semialdehyde dehydrogenases from Pseudomonas putida.
  • Biochimica et Biophysica Acta. 1988 Apr 14;953(3):249-57.

Prieto MI, Martin J, Balaña-Fouce R, Garrido-Pertierra A.

  • Properties of gamma-aminobutyraldehyde dehydrogenase from Escherichia coli.
  • Biochimie. 1987 Nov-Dec;69(11-12):1161-8.

Balaña-Fouce R, Garzón Pulido T, Ordóñez-Escudero D, Garrido-Pertierra A.

  • Inhibition of diamine oxidase and S-adenosylmethionine decarboxylase by diminacene aceturate (berenil).
  • Biochemical Pharmacology. 1986 May 1;35(9):1597-600. No abstract available.

Prieto-Santos MI, Martín-Checa J, Balaña-Fouce R, Garrido-Pertierra A.

  • A pathway for putrescine catabolism in Escherichia coli.
  • Biochimica et Biophysica Acta. 1986 Feb 19;880(2-3):242-4.

Balaña-Fouce R, Ordoñez-Escudero D, Sanz-Sánchez F, Garrido-Pertierra A.

  • Properties of S-adenosylmethionine decarboxylase from rabbit liver: effects of some hydrazone compounds on its activity.
  • Comparative Biochemistry and Physiology B. 1986;83(1):221-5.

Balaña-Fouce R, Pulido TG, Escudero DO, Sanz-Sanchez F.

  • Effects of phenylated compounds of methylglyoxal bis(guanylhydrazone) on diamine oxidase activity from rat small intestine.
  • Comparative Biochemistry and Physiology C Toxicology and Pharmacology. 1986;83(2):419-21.

Balaña-Fouce R, Garzón T, Ordóñez D, Sanz F.

  • Kinetic studies of the inhibitory effect of L-arginine analogous compounds on putrescine oxidase activity from rat small intestine.
  • Archivos de Farmacología y Toxicología. 1985 Dec;11(3):165-70.